Gentiopicroside

Product Specifications

Botanical NameGentiana species
Part UsedRoot
Specification10%-80%-98%
AppearanceYellow to white powder

Gentiopicroside is the primary bioactive bitter marker compound in Gentiana extracts. By activating human bitter taste receptors (hTAS2R38/hTAS2R14), it stimulates gastric acid and bile secretion, enhances gastrointestinal motility, and provides potent hepatoprotective and anti-inflammatory benefits. Commercial raw material specifications range from 10% to 98% purity, precisely quantified via High-Performance Liquid Chromatography (HPLC).

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1. Product Overview

Gentiopicroside, also known as Gentiopicrin, is a naturally occurring secoiridoid glycoside found in Gentiana species. It is a characteristic bioactive marker used in botanical research, herbal extract standardization, and natural product development.

2. Product Specifications

  • Product Name: Gentiopicroside
  • Synonyms: Gentiopicrin
  • CAS No.: 20831-76-9
  • Molecular Formula: C₁₆H₂₀O₉
  • Molecular Weight: 356.32 g/mol
  • Botanical Source: Gentiana species
  • Part Used: Root
  • Specification: Available in high-purity grades; confirm current assay
  • Appearance: Fine powder, typically pale beige to off-white, depending on grade

3. Functional Applications

  • Botanical Standardization: Used as a marker compound for quality assessment of Gentiana-derived ingredients.
  • Natural Product Research: Supports studies of secoiridoid glycosides and their biological properties.
  • Herbal Ingredient Development: Suitable for specialized botanical research and extract characterization.
  • Analytical Applications: Used as a reference or analytical target in HPLC-based ingredient testing.

4. Formulation Combinations

Gentiopicroside can be considered in research and botanical ingredient development alongside:

  • Gentian Extract: For marker-based standardization and extract profiling.
  • Other Gentiana Constituents: Such as swertiamarin and sweroside for comparative botanical analysis.
  • Multi-Herb Extracts: For research into botanical composition and quality consistency.
  • Standardized Botanical Ingredients: For analytical method development and quality-control programs.

Compatibility, stability, and suitability depend on the specific ingredients, extraction process, and intended application.

5. Market Opportunities

Gentiopicroside serves specialized B2B markets in botanical reference compounds, herbal extract standardization, natural product research, and quality-control testing. Demand may come from botanical ingredient manufacturers, analytical laboratories, research organizations, and suppliers developing standardized Gentiana extracts.

High-purity grades and reliable analytical documentation can help support buyers requiring consistent ingredient identification and quality assessment.

6. Quality & Supply

ProMaxBio supports B2B sourcing for botanical ingredients and specialized compounds. Available purity grades, batch specifications, packaging, and documentation can be confirmed upon request.

Contact our team for the current COA, HPLC assay, sample availability, and bulk quotation.

7. FAQ

Q1: What is the CAS number of Gentiopicroside?
A: The CAS number is 20831-76-9.

Q2: What is Gentiopicroside commonly used for?
A: It is commonly used in botanical research, Gentiana extract standardization, and analytical quality-control applications.

Q3: Is Gentiopicroside the same as Gentiopicrin?
A: Yes. Gentiopicrin is a commonly used synonym for Gentiopicroside.

Q4: What purity grades are available?
A: Available grades depend on the current supply. Please contact us to confirm the assay and obtain the corresponding COA.

Q5: Can I request a sample or bulk quotation?
A: Yes. Please share your required purity, quantity, and intended application so our team can check suitable supply options.

Scientific Research Reference

For further scientific information, refer to the following peer-reviewed review of gentiopicroside’s pharmacological properties and research mechanisms.

Reference: Therapeutic efficacy and mechanisms of gentiopicroside in various diseases (2025)

Source: Frontiers in Pharmacology / PubMed Central

External Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12685940/