1. Product Overview
Arctigenin is the primary bioactive aglycone derivative of arctiin, a major active lignan found in the seeds of Arctium lappa L. (Burdock). As the deglycosylated form, it exhibits superior cellular bioavailability and potent biological activity compared to its glycoside precursor. Modern pharmacological evaluations have established its exceptional efficacy in modulating inflammatory pathways, supporting neuroprotection, and regulating cellular metabolism.
Our pharmaceutical-grade Arctigenin is precisely purified to commercial standards ranging from **90.0% to 98.0%**, verified via rigorous high-performance liquid chromatography (HPLC). For B2B formulators, advanced research institutions, and specialized supplement brands, our bulk powder delivers unmatched chemical purity, batch-to-batch reproducibility, and reliable performance in next-generation health products.
2. Product Specifications (Analytical Quality)
| Test Item | Specification Standard | Batch Result | Test Method |
|---|---|---|---|
| Identification (HPLC/MS) | Corresponds to Reference Standard | Conforms | HPLC / MS |
| Assay | 90.0% – 98.0% (High Purity Grade) | 98.3% | HPLC |
| Appearance | White to off-white crystalline powder | Conforms | Visual |
| Loss on Drying | ≤ 1.0% | 0.45% | Gravimetric |
| Residue on Ignition (Ash) | ≤ 0.5% | 0.12% | Gravimetric |
| Heavy Metals (Pb) | < 5 ppm | Conforms | ICP-MS |
| Microbiological Analysis | ≤ 1,000 CFU/g | < 100 CFU/g | USP/EP Standard |
3. Functional Applications
- Advanced Anti-Inflammatory Supplements: Targets specific inflammatory mediators (such as NO and cytokines) at a cellular level, supporting systemic wellness.
- Neuroprotective & Cognitive Health Research: Explored extensively for its capability to support neurological health and protect against cognitive decline pathways.
- Metabolic & Energy Balance Formulations: Assists in regulating lipid metabolism and supporting healthy cellular energy pathways.
- High-End Cosmeceuticals: Integrated into specialized topical anti-aging lines for its remarkable ability to soothe irritated skin and combat oxidative stress.
4. Formulation Combinations
To create synergistic, high-efficacy formulations, Arctigenin pairs exceptionally well with:
- Resveratrol or Quercetin: Amplifies systemic antioxidant defense and cellular longevity signaling.
- Curcumin Phytosome: Combines powerful natural anti-inflammatory agents for enhanced joint and tissue support.
- Piperine (Black Pepper Extract): Enhances overall systemic absorption and bioavailability of the aglycone molecule.
5. Market Opportunities
- Demand for Bioavailable Aglycones: Modern supplement formulators are shifting toward aglycone forms because they bypass the initial deglycosylation step, ensuring superior absorption.
- Targeted Therapeutic Nutriceuticals: Growth in premium market segments seeking scientifically validated, single-molecule botanical actives over crude extracts.
- Longevity & Cellular Health Expansion: Increasing R&D investment into natural lignans that protect neurological and metabolic integrity.
6. Quality & Supply
- Rigorous Analytical Assurance: Verified via high-performance liquid chromatography (HPLC) and mass spectrometry; every commercial batch ships with an official Certificate of Analysis (CoA).
- Packaging & Storage: Packaged in medical-grade amber glass vials or light-blocking double-lined aluminum foil bags (1g, 10g, 100g, 1kg sizes available). Store tightly sealed at -20°C for long-term stability.
- Global Compliance: Manufactured under strict cGMP standards, ensuring full traceability and seamless customs clearance for international research and B2B delivery.
7. FAQ (Frequently Asked Questions)
Q1: What is the difference between Arctiin and Arctigenin?
A1: Arctiin is a glycoside (bound to a sugar molecule), whereas Arctigenin is the aglycone form. Arctigenin is more readily absorbed and represents the direct active metabolite responsible for many of burdock’s pharmacological benefits.
Q2: What purity levels of Arctigenin do you offer?
A2: We supply high-purity commercial grades standardized from 90.0% up to 98.0% via precise HPLC quantification.
Q3: Is Arctigenin soluble in water?
A3: It has very low water solubility and is typically dissolved in organic solvents like DMSO or ethanol, or formulated using lipid/micellar delivery systems for enhanced bioavailability.
8. References
- PubMed: Pharmacological properties and bioavailability of Arctigenin – Comprehensive reviews on anti-inflammatory, neuroprotective, and metabolic mechanisms.
- SpecialChem / Active Ingredients Directory: Arctigenin Profile – Overview of chemical characteristics, stability parameters, and advanced formulation applications.
- Keywords you may search: bulk arctigenin raw material, high purity arctigenin for research and formulations, botanical ingredients with anti-inflammatory properties, how to source standardized arctigenin, HPLC tested arctigenin powder.
