Lycopene

Lycopene (CWD Beadlets 5%-20% / Oil Suspension 6%-20% / Crystal ≥98% USP) | Gold Standard Carotenoid for Prostate Vitality, Cardiovascular Health & Nutricosmetics

1. Product Overview & Value Proposition

Lycopene (all-trans-lycopene, 茄红素 / 番茄红素), an open-chain acyclic carotenoid isomer containing 11 conjugated double bonds, is quantitatively one of the most potent biological antioxidants identified in nutritional science. Unlike beta-carotene, Lycopene possesses unsubstituted beta-ionone rings, meaning it exhibits no provitamin A activity; instead, its entirely conjugated polyene backbone confers an extraordinary physical quenching rate against high-energy singlet oxygen (¹O₂)—quenching singlet oxygen twice as effectively as beta-carotene and over 100 times more potently than alpha-tocopherol (Vitamin E). In mammalian biochemistry, orally ingested lycopene undergoes micellar incorporation and is actively distributed through low-density lipoproteins (LDL), displaying marked organ-specific tropism: it bioaccumulates at concentrations up to 10-fold higher in human prostate tissue, testes, adrenal glands, and liver than in peripheral circulation.

Within clinical urology and healthy aging, Lycopene suppresses insulin-like growth factor-1 (IGF-1) receptor signaling, downregulates pro-inflammatory cytokines, activates the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant pathway, and preserves prostate cellular DNA integrity against oxidative stress. Concurrently, in cardiovascular and dermal physiology, Lycopene prevents the oxidation of circulating LDL particles, promotes flow-mediated endothelial vasodilation via eNOS up-regulation, and mitigates UV-induced erythema. To resolve the inherent instability of polyene carotenoids (which are sensitive to photo-oxidation, heat, and air), we supply specialized, highly stabilized commercial forms:

• Cold-Water-Dispersible (CWD) Microencapsulated Beadlets (5%, 10% & 20%): Spray-agglomerated, beadlet-engineered powders with an outer protective starch/acacia shell and natural tocopherol antioxidants, ensuring excellent bulk density, zero compressibility loss during high-speed direct tableting, and instant, clumping-free dispersion in functional beverages.
• Lipophilic Oil Suspensions (6%, 10% & 20%): Micronized crystalline lycopene dispersed in food-grade sunflower or soybean oil, optimized for direct filling into softgel capsules and oral dropper elixirs.
• Ultra-Pure Crystalline Grade (≥ 96.0%–98.0% HPLC): High-assay, deep violet-red microcrystalline active compliant with USP and European Pharmacopoeia monographs, designed for low-dose clinical formulations and specialized research.

As an established bulk Lycopene manufacturer and direct active ingredient supplier, we extract and refine our material from non-GMO ripe processing tomatoes and bio-fermented Blakeslea trispora using automated low-temperature solvent recovery, molecular crystallization, and high-stability microencapsulation. To empower agile brands and contract manufacturing organizations (CMOs), we pair uncompromising analytical quality with flexible commercial terms: accessible low MOQ procurement for benchtop pilot trials, multi-ingredient shipment consolidation across our urological botanicals, longevity vitamins, and functional mushroom catalog, and dedicated on-the-ground China-wide raw material sourcing assistance tailored to your exact manufacturing requirements.

2. Product Specifications (Analytical Quality)

3. Functional Applications (Mechanism of Action)

Deploying pharmaceutical-grade Lycopene across men’s urological formulas, cardiovascular supplements, and nutricosmetic photoprotection elixirs provides clinically validated biological mechanisms:

• Potent Singlet Oxygen Quenching & Radical Scavenging: The extended 11-conjugated polyene chain of Lycopene acts as an efficient physical quencher of singlet oxygen (¹O₂) without molecule degradation. It dissipates the excess excitation energy of singlet oxygen directly into vibrational and thermal energy, inhibiting lipid peroxidation in cellular plasma membranes and preventing reactive oxygen species (ROS)-induced DNA strand breaks.
• Targeted Prostate Bioaccumulation & IGF-1 Modulation: Lycopene selectively crosses prostatic capillary beds, reaching intraprostatic tissue concentrations up to ten times higher than in circulating plasma. In prostate stroma and epithelial cells, it downregulates insulin-like growth factor-1 (IGF-1) receptor phosphorylation, upregulates connexin 43 to restore gap-junction intercellular communication (GJIC), and inhibits abnormal prostatic tissue expansion.
• Protection of Low-Density Lipoprotein (LDL) from Oxidation: In systemic circulation, Lycopene is incorporated into the hydrophobic core of LDL particles. By scavenging lipid peroxyl radicals, it prevents the oxidative conversion of native LDL into atherogenic oxidized LDL (ox-LDL), shielding vascular endothelial walls against macrophage scavenger receptor uptake, foam-cell accumulation, and arterial plaque formation.
• Endothelial Nitric Oxide Synthase (eNOS) Upregulation: Stimulates eNOS phosphorylation in vascular endothelial cells, preserving endogenous nitric oxide (NO) bioavailability and reducing vascular cell adhesion molecule-1 (VCAM-1) expression. This promotes arterial flow-mediated dilation (FMD) and supports healthy systolic blood pressure.
• Cutaneous Photo-Protection & Anti-Erythema Defense: When orally consumed over 8 to 12 weeks, Lycopene accumulates within the epidermal and dermal layers, acting as an internal biological photoprotective shield. Clinical trials show that daily lycopene supplementation decreases UV-induced skin erythema (sunburn response) by up to 35%–40%, suppresses matrix metalloproteinase-1 (MMP-1) collagen breakdown, and prevents solar photoaging.
• Stable Natural Color & Antioxidant Defense in “Mushroom Coffee”: Microencapsulated CWD Lycopene Beadlets disperse smoothly into functional mushroom coffee and adaptogenic drink sticks. It contributes a rich, warm reddish undertone, neutralizes free radicals generated during high-temperature roasting, and provides daily prostate-cardio cellular defense without imparting a bitter or cooked-tomato flavor.

4. Formulation Combinations & Trending Market Applications

Capitalize on the expanding functional beverage, men’s urological health, and nutricosmetic longevity markets by formulating with our versatile Lycopene portfolio:

• The Master Clinical Prostate & Urological Vitality Softgel Matrix: Our Lycopene (10% Oil Suspension, 150 mg delivering 15 mg active lycopene) + Saw Palmetto Supercritical CO₂ Oil (85%–90% Fatty Acids, 320 mg) + Pygeum Africanum Extract (13% Phytosterols, 100 mg) + Beta-Sitosterol (≥70%, 100 mg) + Zinc Glycinate (15 mg elemental Zn) + Selenium (as L-Selenomethionine, 55 μg). The gold-standard clinical urological formula: Saw Palmetto and Beta-Sitosterol downregulate 5α-reductase and DHT, Pygeum halts bFGF-driven stromal cell hyperplasia, and Lycopene protects prostate cellular DNA against oxidative insult.
• The Cardiovascular Endothelial & Anti-Atherosclerosis Stack: Our Lycopene (CWD Beadlets 10%, 100 mg delivering 10 mg lycopene) + Coenzyme Q10 (Ubiquinone 98%, 100 mg) + Phytosterols (≥95%, 800 mg) + Alpha-Glucosyl Hesperidin (≥85%, 100 mg) + Grape Seed Extract (OPC 95%, 100 mg). A comprehensive vascular health formula pairing micellar cholesterol displacement with targeted LDL lipid peroxidation defense, CoQ10 bioenergetics, and microcapillary dilation.
• The “Internal Sunscreen & Radiant Youth” Nutricosmetic Sachet: Our Lycopene (CWD Beadlets 10%, 100 mg) + Hydrolyzed Marine Collagen Peptides (3,000–5,000 mg) + Natural Astaxanthin Powder 2% (200 mg delivering 4 mg active astaxanthin) + L-Ergothioneine (≥99%, 5 mg) + Vitamin C (100 mg). A premium beauty-from-within drink packet designed to shield dermal collagen from UV-induced MMP-1 degradation, reduce sun-induced redness, and restore skin elasticity and radiance.
• The Men’s Morning Adaptogenic “Prostate & Energy” Mushroom Coffee: Our Lycopene (CWD Powder 5%, 200 mg delivering 10 mg active lycopene) + Cordyceps Militaris Extract (Cordycepin 1%, 300 mg) + Lion’s Mane Mushroom Extract (Beta-Glucan 30%, 300 mg) + Maca Root Extract (10:1, 300 mg) + Micro-Ground Arabica Coffee. A high-value functional morning beverage delivering foundational male cellular defense, ATP stamina, and sharp executive mental focus without caffeine jitters or midday crashes.

5. Why Choose Us As Your Long-Term Active Ingredient Partner?

• Flexible Low MOQ Policy: Mitigate product launch risk. As an agile low MOQ Lycopene bulk supplier, our orders start as low as 1 kg for standardized CWD beadlets (5%–20%), oil suspensions (6%–20%), and pure crystalline powders (≥98%), scaling smoothly up to recurring multi-ton commercial container contracts.
• Multi-Product Portfolio Consolidation: Streamline your procurement by sourcing your complete men’s health suite (Lycopene, Saw Palmetto, Pygeum Africanum, Beta-Sitosterol, Pumpkin Seed, Tongkat Ali), longevity vitamins (L-5-MTHF-Ca, β-NMN), and functional mushrooms (Cordyceps, Lion’s Mane, Reishi) under a single, cost-effective freight shipment to reduce customs overhead and landed freight costs.
• Value-Added China Sourcing Service: In addition to our dedicated carotenoid crystallization facilities and microencapsulation spray towers, our on-the-ground technical team audits agricultural tomato-paste supply chains, validates HPLC isomer testing paperwork, and procures specialized functional ingredients across China tailored to your exact manufacturing roadmap.

6. Quality & Supply Chain Assurance

• Traceable Non-GMO Tomato & Fungal Sources: Sourced strictly from non-GMO high-lycopene industrial processing tomatoes (*Solanum lycopersicum*) grown in the sunny agricultural basins of Xinjiang and northern China, or clean microbial bio-fermentation (*Blakeslea trispora*). Both sources are verified identity-preserved and free from genetically modified DNA.
• Advanced Microencapsulation & Beadlet Engineering: Native lycopene is highly prone to oxidation and isomerization into degraded fragments. Our CWD beadlets utilize a gelatin/acacia gum and modified food starch matrix containing natural dl-alpha-tocopherol and ascorbyl palmitate antioxidants, ensuring complete shelf-life stability, zero color bleeding, and robust survival during high-pressure tableting.
• Strict Compliance with USP Isomer Profiling: Tested against official USP reference standards via validated normal-phase or reversed-phase High-Performance Liquid Chromatography (HPLC-UV at 472 nm). We strictly quantify all-E-lycopene (≥65%–70%) and ensure 5Z-lycopene stays below 23%, confirming full bio-potency and absence of synthetic degradation artifacts.
• Total Solvent Residue Control: Extracted using closed-loop food-grade solvents (ethyl acetate, ethanol, or acetone) followed by vacuum crystallization. All finished grades are verified via Gas Chromatography Headspace (GC-HS) to comply with USP <467> and European Pharmacopoeia limits, leaving zero harmful petrochemical residues.
• Comprehensive ICP-MS & Pesticide Screening: Batch-tested via high-resolution ICP-MS and GC-MS/MS to ensure heavy metals (Lead, Arsenic, Cadmium, Mercury) and agrochemical residues strictly comply with California Prop 65, USP <561>, and European Union food supplement standards. Packaged under inert nitrogen gas blankets in vacuum-sealed aluminum barrier pouches and heavy-duty 25 kg fiber export drums.

7. FAQ

Q1: What is the primary difference between Tomato-Derived Lycopene and Fermentation-Derived Lycopene (Blakeslea trispora)?
A1: Both sources deliver identical, chemically defined lycopene (C₄₀H₅₆) compliant with USP and European Pharmacopoeia monographs:

• Tomato Extract: Derived from the fruit pulp of Solanum lycopersicum. It naturally contains minor levels of secondary tomato phyto-nutrients (such as phytoene, phytofluene, and tocopherols), preferred by brands seeking whole-food botanical origin claims on consumer labels.
• Blakeslea trispora Fermentation: Produced via non-GMO microbial co-fermentation of fungal mating types. It yields exceptionally high purity (≥96%–98% crystal), provides complete harvest independence from weather fluctuations, and offers exceptional batch consistency at a competitive commercial price point.

Q2: Why does Lycopene selectively accumulate in the human Prostate Gland?
A2: In human physiology, lycopene is transported via low-density lipoproteins (LDL) and high-density lipoproteins (HDL). Prostate epithelial tissue expresses high densities of scavenger receptor class B type I (SR-BI) and LDL receptors that actively clear circulating carotenoids. Consequently, lycopene bioaccumulates in human prostate stroma and epithelial cells at concentrations up to 10-fold higher than in peripheral blood, serving as a vital front-line antioxidant against prostatic cellular DNA mutations and oxidative stress.

Q3: Which commercial form of Lycopene should I choose for my finished product format?
A3: Formulation choice depends on the final delivery system:

• CWD Microencapsulated Beadlets (5%–20%): The premier choice for two-piece hard capsules, direct-compression multivitamin tablets, and powdered drink sachets (dissolves cleanly in water into a stable, non-staining red/pink dispersion).
• Oil Suspension (6%–20%): The industry benchmark for soft gelatin and vegan liquid-filled capsules, lipophilic droppers, and oil-based nutritional blends.
• Pure Crystal (≥98%): Used for specialized clinical research, low-dosage active premixes, and high-precision pharmaceutical-grade applications.

Q4: How does Lycopene act as an “Internal Sunscreen” for skin photoprotection?
A4: Dietary lycopene is transported into dermal and epidermal cell membranes. When skin is exposed to solar UVA/UVB radiation, reactive singlet oxygen and free radicals are generated. Lycopene physically quenches these radicals before they can damage cellular DNA or trigger inflammatory sunburn cascades, reducing skin redness (erythema) and suppressing matrix metalloproteinases (collagenase) to prevent UV-induced wrinkles and collagen loss.

Q5: What is the MOQ for bulk Lycopene orders?
A5: We support agile commercialization with minimum order quantities starting from just 1 kg for standardized CWD beadlets (5%–20%), oil suspensions (6%–20%), and pure crystalline powders (≥98%), scaling smoothly up to recurring multi-ton commercial manufacturing contracts.

8. References

1. PubChem: Lycopene Compound Summary (CID 446925) – National Center for Biotechnology Information.
2. PubMed Central: Lycopene in Human Health: Mechanisms of Action, Prostate Cancer Risk Reduction, and Cardiovascular Protection: A Comprehensive Review – National Institutes of Health research database.

Keywords you may search: bulk Lycopene supplier, tomato extract lycopene manufacturer, lycopene 10 percent CWD beadlets, lycopene oil suspension 20 percent bulk, pure lycopene crystal 98 percent USP, prostate health antioxidant raw material, internal sunscreen lycopene nutricosmetic, Blakeslea trispora fermentation lycopene, low MOQ carotenoid provider, custom China ingredient sourcing service, pure lycopene bulk