Product Overview
Mulberry Leaf Extract is derived from the leaves of Morus alba (white mulberry), a tree with centuries of documented use in traditional herbal practices and modern phytotherapy. The principal bioactive compound responsible for its remarkable physiological activity is 1-Deoxynojirimycin (1-DNJ), a unique natural polyhydroxylated alkaloid (iminosugar) that acts as a potent alpha-glucosidase inhibitor.
Promaxbio offers premium-grade Mulberry Leaf Extract standardized via High-Performance Liquid Chromatography (HPLC) to guarantee consistent 1-DNJ concentrations (ranging from 1.0% to 5.0%). Sourced from carefully cultivated white mulberry leaves and processed under strict cGMP standards, our extract provides B2B dietary supplement manufacturers and functional formulators with a reliable, high-purity raw material tailored for modern metabolic health and glycemic control.
Product Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Mulberry Leaf Extract | Visual |
| Botanical Name | Morus alba L. | Taxonomic Identity |
| Active Marker | 1-Deoxynojirimycin (1-DNJ) ≥ 1.0% – 5.0% | HPLC |
| Part Used | Leaf | Visual |
| Appearance | Greenish-brown to light yellow-brown fine powder | Organoleptic |
| Odor & Taste | Characteristic, slightly bitter | Organoleptic |
| Particle Size | 100% pass 80 mesh | USP <786> |
| Loss on Drying | ≤ 5.0% | USP <731> |
| Total Ash | ≤ 5.0% | USP <561> |
| Heavy Metals (as Pb) | ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 2 ppm) | ICP-MS |
| Microbiological Profile | Total Plate Count < 1,000 CFU/g; Yeast & Mold < 100 CFU/g; E. coli / Salmonella Negative | USP <2021/2022> |
Functional Applications
- Healthy Glycemic Support: Competitively inhibits intestinal alpha-glucosidase enzymes, slowing down the digestion and absorption of complex carbohydrates and simple sugars.
- Postprandial Blood Sugar Regulation: Helps blunt post-meal blood glucose and insulin spikes, supporting smooth metabolic equilibrium throughout the day.
- Metabolic Wellness & Weight Management: Assists in managing carbohydrate utilization and caloric impact, making it an ideal companion for weight control formulations.
- Antioxidant & Vascular Defense: Rich in polyphenols and quercetin derivatives that help neutralize free radicals and protect cardiovascular tissues from oxidative stress.
Formulation Combinations
- Blood Sugar & Carb-Blocking Stacks: Synergizes effectively with White Kidney Bean Extract, Gymnema Sylvestre Extract, and Berberine HCl for comprehensive glycemic control.
- Metabolic & Weight Management Blends: Pairs seamlessly with Green Tea Extract (EGCG) and Chromium Picolinate for multi-action metabolic capsules.
- Longevity & Healthy Aging Matrices: Formulated alongside anti-aging botanical extracts to support overall metabolic longevity and cellular defense.
Market Opportunities
- Glycemic Health & Anti-Sugar Trend: Massive global consumer demand for natural, plant-based ingredients that help mitigate the effects of high-carb modern diets.
- Synergistic Carb-Blocker Sector: High market synergy when combined with traditional starch-blockers like white kidney bean, creating comprehensive dual-action formulas.
- Standardized Potency Options: B2B formulators can select specific 1-DNJ titers (1% to 5%) to optimize capsule size, dosing precision, and price positioning.
Quality & Supply Assurance
Promaxbio guarantees strict cGMP-compliant manufacturing for every commercial batch of Mulberry Leaf Extract. Our material undergoes rigorous HPLC assay testing, heavy metal screening via ICP-MS, and complete microbiological verification. Packaged in food-grade polyethylene bags inside secure fiber drums, our product is fully protected against moisture, light, and degradation during storage and international transit.
Frequently Asked Questions (FAQ)
Q1: What makes 1-DNJ in mulberry leaves unique?
A: 1-Deoxynojirimycin (1-DNJ) is a rare natural iminosugar whose molecular structure mimics glucose, allowing it to fit perfectly into alpha-glucosidase enzyme active sites and temporarily slow down sugar absorption in the gut.
Q2: How should Mulberry Leaf Extract be incorporated into supplements?
A: It is typically formulated into capsules or powder drink mixes and recommended to be taken right before carbohydrate-containing meals for maximum glycemic support.
References & Scientific Literature
- Kimura, T., et al. (2007). Administration of 1-deoxynojirimycin-rich mulberry leaf extract affects postprandial blood glucose responses in humans. Journal of Agricultural and Food Chemistry, 55(4), 1239–1243. DOI: 10.1021/jf0626799
- Asano, N., et al. (2001). Dietary azasugars from Morus alba and Salacia species: their occurrence and biological activity. Current Topics in Medicinal Chemistry, 1(6), 541–554. DOI: 10.2174/1568026013394787
