Product Overview
Rutin (also known as rutoside, sophorin, or quercetin-3-rutinoside) is a natural glycoside formed between the flavonol quercetin and the disaccharide rutinose. It is abundantly found in the dried flower buds of Sophora japonica (Japanese Pagoda tree), which serves as the primary commercial source for high-purity industrial extraction.
Promaxbio offers pharmaceutical and nutraceutical-grade Rutin standardized to a minimum purity of 95% or 98% via High-Performance Liquid Chromatography (HPLC) and UV spectrophotometry. Manufactured under strict cGMP guidelines, our Rutin powder provides B2B dietary supplement brands, functional food formulators, and cosmetic manufacturers with a reliable, high-purity bioactive ingredient tailored for vascular health, circulatory support, and advanced antioxidant formulations.
Product Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Rutin (Sophora Japonica Extract) | Visual |
| Botanical Name | Sophora japonica L. | Taxonomic Identity |
| Assay (Purity) | Rutin ≥ 95.0% or 98.0% | HPLC / UV |
| Part Used | Flower Bud | Visual |
| Appearance | Yellow to light green-yellow crystalline powder | Organoleptic |
| Odor & Taste | Characteristic, bland | Organoleptic |
| Particle Size | 100% pass 80 mesh | USP <786> |
| Loss on Drying | ≤ 5.0% | USP <731> |
| Heavy Metals (as Pb) | ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 2 ppm) | ICP-MS |
| Microbiological Profile | Total Plate Count < 1,000 CFU/g; Yeast & Mold < 100 CFU/g; E. coli / Salmonella Negative | USP <2021/2022> |
Functional Applications
- Vascular & Capillary Health: Strengthens capillary walls, reduces vascular permeability, and supports healthy microcirculation and venous tone.
- Powerful Antioxidant Defense: Scavenges free radicals, protects cellular structures from oxidative stress, and works synergistically with vitamin C.
- Circulatory & Joint Comfort: Assists in managing minor swelling, heavy legs, and promotes overall circulatory wellness.
- Cosmetic Skin Protection: Incorporated into topical anti-aging and anti-redness skincare products to protect against UV-induced oxidative damage and support skin micro-vessels.
Formulation Combinations
- Circulatory & Vein Health Stacks: Synergizes effectively with Diosmin, Hesperidin, and Horse Chestnut Extract for comprehensive venous and leg health capsules.
- Antioxidant & Immune Blends: Pairs seamlessly with Vitamin C and Bioflavonoids to maximize systemic free-radical scavenging.
- Advanced Longevity Matrices: Formulated alongside Quercetin and Resveratrol for holistic cardiovascular and cellular defense.
Market Opportunities
- Vascular Support Sector: High and steady global demand for natural bioflavonoids addressing chronic venous insufficiency and circulatory maintenance.
- Cost-Effective Bioactive: Offers high purity and clinical reliability at an excellent cost-efficiency ratio for large-scale supplement production.
- Dual Industry Utility: Widely accepted across both the dietary supplement industry (capsules/tablets) and the cosmetic industry (anti-redness and vascular skincare).
Quality & Supply Assurance
Promaxbio guarantees strict cGMP-compliant manufacturing for every commercial batch of Rutin. Our material undergoes rigorous HPLC assay testing, heavy metal screening via ICP-MS, and complete microbiological verification. Packaged in light-resistant, food-grade polyethylene bags inside secure fiber drums, our product is fully protected against moisture and degradation during storage and global transit.
Frequently Asked Questions (FAQ)
Q1: What is the relationship between Rutin and Quercetin?
A: Rutin is a glycoside of quercetin (quercetin bound to rutinose). In the human body, digestive enzymes break down it into quercetin, allowing it to provide systemic antioxidant and vascular benefits.
Q2: What are the typical commercial grades available?
A: Promaxbio primarily supplies 95% and 98% purities, which are optimized for dietary supplement capsules, tablets, and high-end cosmetic formulations.
References & Scientific Literature
- Ganeshpurkar, A., & Saluja, A. K. (2017). The pharmacological potential of rutin. Saudi Pharmaceutical Journal, 25(2), 149–164. DOI: 10.1016/j.jsps.2016.04.025
- Chung, Y. K., et al. (2006). Anti-inflammatory effect of rutin and its derivative in microglial cells. Free Radical Research, 40(6), 619–628. DOI: 10.1080/10715760600619087
