💡 Product Overview (TL;DR)
Dihydromyricetin (DHM), also known as Ampelopsin (CAS 27200-12-0), is a high-purity natural dihydroflavonol extracted from the tender stems and leaves of Ampelopsis grossedentata (Vine Tea / Teng Cha). Promaxbio supplies standardized DHM with 98% HPLC purity. It is globally renowned for its exceptional efficacy in accelerating alcohol metabolism (enhancing ADH/ALDH activity), preventing alcohol-induced hangovers, shielding hepatocytes from oxidative damage, and supporting metabolic health.
1. Product Specifications & Technical Standards
| Specification Grade | Assay Standard (HPLC) | Physical Appearance | Primary Application |
|---|---|---|---|
| Standard Grade (50% – 80%) | DHM ≥ 50.0% – 80.0% | Light yellow to brown powder | Cost-effective herbal teas, general dietary wellness blends |
| High-Purity Grade (98%) | DHM ≥ 98.0% (HPLC) | Off-white to white fine powder | Anti-hangover capsules, advanced liver protection, premium nootropic formulas |
2. Functional Applications & Mechanisms of Action
- Rapid Alcohol Metabolism & Hangover Relief: DHM accelerates the breakdown of ethanol and acetaldehyde by up-regulating ADH and ALDH enzyme activity, preventing GABA receptor rebound and eliminating morning-after hangover symptoms.
- Hepatoprotection & Liver Detox: Suppresses lipid peroxidation, activates the Nrf2 antioxidant pathway, and reduces elevated liver enzymes (ALT/AST) caused by alcohol, toxins, or fatty liver.
- Metabolic & Blood Sugar Regulation: Improves insulin sensitivity and regulates glucose-lipid metabolism via AMPK pathway activation.
- Neuroprotection & Anti-Inflammatory: Crosses the blood-brain barrier to reduce neuroinflammation, protecting neurons from oxidative stress and cognitive fatigue.
3. Synergistic Formulation Combinations
- Ultimate Anti-Hangover & Liver Recovery Complex: DHM (98%) + Myricitrin + Milk Stistle (Silymarin 80%) + Curcumin Phytosome.
- Metabolic & Blood Sugar Support Blend: DHM (98%) + Berberine + Chromium Picolinate + Mulberry Leaf Extract.
4. Market Opportunities & Consumer Trends
Driven by the booming “Social Wellness” and “Longevity” sectors, Dihydromyricetin has transitioned from a niche botanical into a mainstream blockbuster ingredient in North America, Europe, and Asia. It powers modern functional gummies, effervescent hangover recovery tablets, and clinical-grade liver health capsules.
5. Quality Assurance, Supply & OEM Services
At Promaxbio, we ensure strict compliance with international quality and safety benchmarks:
- Analytical Validation: Verified via HPLC-DAD (98% purity confirmed).
- Heavy Metals & Microbiology: Compliant with USP <232>/<233> and USP <2021>/<2022> limits (Lead ≤ 2.0 ppm, zero Salmonella/E. coli).
- Flexible Commercial Support: Low MOQs available for pilot runs; full OEM/ODM private label capsule and tablet manufacturing services supported globally.
6. Frequently Asked Questions (FAQ)
Q1: What is the recommended daily dosage for DHM 98%?
For anti-hangover and liver support, typical dosages range from 300 mg to 600 mg taken before or during alcohol consumption, or 150 mg to 300 mg daily for general wellness.
Q2: Is Promaxbio’s DHM natural or synthetic?
Our DHM is 100% naturally extracted and purified from wild-harvested Ampelopsis grossedentata (Vine Tea) leaves and stems.
Scientific Reference
For further scientific information on dihydromyricetin (DHM), including its biological activities, potential applications, and research prospects, please refer to this open-access review published in Evidence-Based Complementary and Alternative Medicine.
Reference: The Versatile Effects of Dihydromyricetin in Health – Full Text
